Indian Institute of Science have identified 29 drugs for Covid-19 patients

Indian Institute of Science have identified 29 drugs for Covid-19 patients

Indian Institute of Science have identified 29 drugs for Covid-19 patients
29 drugs for Covid-19 patients

Researchers at Indian Institute of Science (IISc) have identified at least 29 drugs that have the potential of being repurposed to treat Covid-19 patients.


“Covid-19 has almost brought normal life to a standstill in most parts of the world. With our research interest on repurposing known drugs/drug candidates targeting various diseases, we decided to analyse the available data on the deadly pathogen,” the team said. 


The team, comprising Prof Narayanaswamy Srinivasan (leader), Sohini Chakraborti and Sneha Bheemireddy, has identified 29 potential repurpose-able agents that are either approved and/or investigational drugs.


This was achieved using a simple in silico (performed on computer) approach based on the principle of ‘neighbourhood behaviour’ in three-dimensional (3D) space and two-dimensional (2D) space of protein and small molecules respectively.


“Using this, we identified potential drugs/drug candidates which can be repurposed against protein targets encoded by the SARS-CoV-2 [the virus that causes Covid-19] genome,” the researchers said. “And, based on our preliminary analysis, we have so far prioritized more than 20 known drugs/drug candidates which might elucidate anti-coronavirus properties by binding to the main protease of the pathogen.” The team also said they have identified nine other investigational drug molecules.